Gone with a shot? {Health issue}

Context

This article talks about the drug which has been recently approved to cure migraines.

In news

Recently the first medicine designed to prevent migraines was approved by the Food and Drug Administration (FDA) , many experts believe will be a new era in treatment for people who suffer the most severe form of these headaches.

About the drug

The drug, Aimovig, made by Amgen and Novartis, is a monthly injection with a device similar to an insulin pen.

How does it work?

Aimovig blocks a protein fragment, CGRP, that instigates and perpetuates migraines.

Background

The idea behind the new drugs dates to the 1980s when researchers noticed that the protein fragment CGRP seemed to play a role in migraines. It transmits signals between nerves and also dilates blood vessels.

Millions of people experience severe migraines so often that they are disabled and in despair. These drugs do not prevent all migraine attacks, but can make them less severe and can reduce their frequency by 50% or more.

A cause of disability

One in 7 people worldwide experience migraines — as many as 20% of women, and 10% of men. About 2% of the global population copes with chronic migraines. By some estimates, migraine is the third most common disease in the world, and it ranks among the top 10 causes of disability.

It is not just a headache: A migraine often is accompanied by disabling symptoms such as nausea and vomiting, difficulty speaking, and an aversion to light and noise. The headache can be throbbing and last for hours or days.

Migraine

Migraines are severe, recurring, and painful headaches. They can be preceded or accompanied by sensory warning signs and other symptoms.

Fast facts on migraines

  • Some people who experience migraines can clearly identify triggers or factors that cause the headaches, such as allergies, light, and stress.
  • Some people get a warning symptom before the start of a migraine headache.
  • Many people with a migraine can prevent a full-blown attack by recognizing and acting upon the warning signs.
  • Over-the-counter (OTC) medications can eliminate or reduce pain, and specific medications can help some people with a migraine.
  • People who have severe attacks can take preventive medicines.

 

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